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DETOXIFICATION: Supports the removal of toxins and can help protect other antioxidants such as vitamins C and E, promoting an increase in energy production

Trimethoprim-Sulfamethoxazole The trimethoprim-sulfamethoxazole (TMP-SMZ) class of antibiotics fights bacterial infections by hindering the bacterias ability to use folate, an important B vitamin, according to Ebsco

That means MPs affect the fishs behavior, physiology, and metabolism and interfere with the disease resistance in fish populations upon MP accumulation (Mattsson et al., 2015)

So for chronic degenerative conditions, my bias is to avoid it, and my bias strengthens the longer someone wants to use it